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Vision Leads to Action

Mechanically Enhanced Colonoscopy

ENDOCUFF VISION® is a device attached to the distal end of a colonoscope, designed to maintain and maximize the viewable mucosa during endocosopic therapy by manipulating colonic folds. A single row of flexible arms evert and flatten folds to provide an enhanced view of the entire colon and increase polyp and adenoma detection rate.

Physician Benefits

Improved Visualization
Upon withdrawal, the uniquely hinged arms expand to gently flatten large mucosal folds, bringing difficult-to-see areas into view. Soft, flexible arms provide the right amount of force to be effective without causing mucosal trauma.

Increased Adenoma Detection Rate
The use of ENDOCUFF VISION resulted in a statistically significant and clinically relevant increase in ADR.

Improved Control
Anchors endoscope tip during examination and polypectomy and reduces slippage and looping.

Improved Design
The proprietary hinged design allows the arms to fall flat against the scope for smooth intubation.

Improved Application
Hard plastic body and firm, dry grip on the scope to prevent dislodgement and protect the distal tip of the colonoscope. Hinged arms fits seamlessly into device to create a low-profile design.

Detection Means Prevention

Increasing adenoma detection rate (ADR)
improves your ability to save lives

  • A 1% increase in ADR results in a 3% decrease in the risk of interval cancer and a 5% decrease in the risk of a fatal interval colorectal cancer1
  • Increasing ADR not only lowers mortality rates but also reduces treatment costs2
1. Corley DA, Jensen CD, Marks AR, et al. Adenoma Detection Rate and Risk of Colorectal Cancer and Death. N Engl J Med. 2014;370(14):1298-1306.
2. Meester RG, Doubeni CA, Lansdorp-Vogelaar I, et al. Variation in Adenoma Detection Rate and the Lifetime Benefits and Cost of Colorectal Cancer Screening: A Microsimulation
Model. JAMA. 2015;313(23):2349-2358.

Clinical Overview

ENDOCUFF VISION has been shown to improve ADR over
standard colonoscopy*

Improved Adenoma Detection with Endocuff Vision: The ADENOMA Randomised Controlled Trial.

Matthew D Rutter, Gayle Clifford, Nicola Totton, Thomas J lee, Arvind Ramadas, John G Silcock, John Painter, Laura J Neilson, Brian P Saunders, Colin J Rees. Gut

Published Online First: 23 January 2018.

Cap cuff – Assisted Colonoscopy Versus Standard Colonoscopy for Adenoma Detection: A Randomized Back-to-Back Study.

De Palma GD, Giglio MC, Bruzzese D., Gennarelli N., Maione F., Siciliano S., Manzo B., Cassese G., Luglio G. Gastrointest Endosc.

2018 Jan;87(1):232-240.

Endocuff­ Assisted Colonoscopy Outperforms Conventional Colonoscopy to Detect Missed­ Adenomas: European Multicenter, Randomized, Back­ to ­Back Study.

Triantafyllou K, Polymeros D, Apostolopoulos P, Lopes Brandao C, Gkolfakis P, Repici A, Papanikolaou IS, Dinis-Ribeiro M, Alexandrakis G, Hassan C., Endoscopy.

2017 Nov;49(11):1051-1060.

Higher Adenoma Detection Rate with Endocuff:
A Randomized Controlled Trial.

David García, Coty Gonzalez-Fernandez, Rafael Barreto-Zuñiga, Nancy E. Aguilar-Olivos, Adriana F. Romano, Guido Grajales-Figueroa, Felix I. Tellez-Avila Gastrointestinal Endoscopy, National Institute of Medical Sciences and Nutrition “Salvador Zubiran”, Mexico City, Mexico

May 2016 Volume 83, Issue 5, Supplement, Page AB193

*Tsiamoulos ZP, Ravi M, et al. Impact of a new distal attachment on colonoscopy performance in an academic screening center. GIE Journal. 2017

Dr. Doug Rex Video Series

“If you're highly tuned into efficiency and you're saving a minute or two per procedure, you may be able to translate that into effective use of your time for something else. Conceivably by the end of the day. Even adding an additional procedure.”

– Dr. Doug Rex
Episode 1:
Economic Benefit of ECV
Episode 2:
and its Benefits
Episode 3:
Adenoma Detection Rate
Episode 4:
Patient Benefits

The Art of Unfolding Webinars

Watch these webinars to learn more about the latest clinical data on mucosal exposure devices and to understand how enhanced colonoscopy using the ENDOCUFF VISION can benefit physicians and patients.
Webinar with Dr. Seth Gross
Webinar with Dr. Doug Rex

Patient Benefits

Lower Polyp & Adenoma Miss Rate
Studies show that up to 24% of adenomas are missed with standard colonscopy. Accurate colon screening with improved visualization from the ENDOCUFF VISION lowers the polyp
and adenoma miss rate and might prevent fatal cancer. Detection saves lives.

Less Mucosal Trauma, Less Pain
The improved design of ENDOCUFF VISION allows smoother forward movement, meaning easy colonoscopy with less pain and less mucosal trauma.

Colonoscopy Overview

Colonoscopy is able to detect early problems that could lead to colon cancer. During this simple and safe procedure, your doctor will use a small flexible tube with a light and camera at the end, called a “colonoscope.” This helps the doctor to view your colon and rectum, looking for abnormalities called “polyps”. If there are any abnormal or cancerous polyps present, your doctor may remove them or take a biopsy through the colonoscope.

The lining of the colon has several folds so it can be difficult for the physician to see behind them and some abnormalities can be missed.


What is Adenoma Detection Rate?

An adenoma is a type of polyp or growth that is identified and can usually be removed during a colonoscopy. Most colon cancers develop from cancerous adenomas. If a benign adenoma is left to grow in the colon, it can become cancerous over time.

Adenoma detection rate (ADR) is currently the best “report card” for colonoscopy performance available. A doctor's adenoma detection rate is the proportion of individuals undergoing a complete screening colonoscopy who have one or more adenomas, or polyps, detected.

When considering a doctor for a colonoscopy, potential patients should be looking for a doctor with an adenoma detection rate of at least 20% in women and 30% in men.


Why is this important?

Colon cancer is 95% curable if it’s discovered early.

Studies show that for each 1% increase in the rate of detection, there’s a 3% reduction in the risk of cancer between colonoscopy screenings. There is also 5% reduction in the risk of fatal colon cancer.

Increasing adenoma detection rate (ADR) improves a physician’s ability to detect cancer at an early stage.

*Corley DA, Jensen CD, Marks AR, et al. Adenoma Detection Rate and Risk of Colorectal Cancer and Death.
N Engl J Med, 2014;370(14)1298-1306


The ENDOCUFF VISION gets fitted onto the end of the colonoscope, and during the procedure these arms open
and flatten out the colon walls so the doctor can better see lesions that might be cancer.

These devices do not increase the length of the procedure or cause discomfort.

Talk to your doctor about ENDOCUFF VISION and how it can ensure an optimal inspection of the colon during colorectal cancer screening.


The ENDOCUFF VISION is intended to be attached to the distal end of the endoscope to facilitate endoscopic therapy, to be used for the following:
  • Keeping the suitable depth of the endoscope’s view field.
  • Helping the endoscope with being inserted into the gastrointestinal tract.


  • The ENDOCUFF VISION is not intended for deep ileal intubation.
  • The ENDOCUFF VISION should not be used in cases with acute, severe colitis or where there is known colonic stricture.
  • The ENDOCUFF VISION should or shall not be used for complex sub-mucosal dissection where a separate distal attachment is required.